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Filtered Search Results
TARGETMOL CHEMICALS INC Oxypurinol 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure. Purity 100%
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Apexbio Technology LLC NP118809 41332-24-5 200mg
NP118809 (CAS 41332-24-5) is a potent and selective blocker of N-type voltage-gated calcium channels exhibiting an IC50 of 0 11 M in vitro It demonstrates significant selectivity over L-type calcium channels with over 100-fold preference (L-type IC50 12 2 M) In vivo studies in rats indicate that NP118809 is orally bioavailable (mean 30%) with a Tmax of 2 3 hours and a half-life of 2 1 hours following intravenous or oral administration The compound exhibits wide tissue distribution and has been shown to produce analgesic effects in animal pain models NP118809 is useful for research into N-type calcium channel function and modulation particularly in studies of pain signaling and neuropharmacology
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Apexbio Technology LLC CYT387 1056634-68-4 200mg
CYT387 (CAS 1056634-68-4) is an aminopyrimidine derivative identified through high-throughput screening and optimized with structure-guided medicinal chemistry It functions as an inhibitor targeting Janus kinase family enzymes JAK1 JAK2 JAK3 and TYK2 with reported IC50 values of 11 nM 18 nM 155 nM and 17 nM respectively At concentrations between 500 1500 nM CYT387 selectively suppresses JAK2 signaling inhibits proliferation of JAK2-dependent hematopoietic cell lines and induces apoptosis with minimal effects on non-hematopoietic cells CYT387 is employed in experimental studies of JAK2-mediated signaling pathways and myeloproliferative neoplasms
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TARGETMOL CHEMICALS INC SAG 10MG
502694121 SAG 10MG
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Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | 600.74 g·mol⁻1 | C29H32D5N7O5S | 5 MG
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Dosimertinib-d5 mesylate is the deuterated mesylate salt of an EGFR inhibitor intended for preclinical research. It is reported to reduce phosphorylation of EGFR and ERK, show antiproliferative and antitumor activity in model systems, and is used in studies of non-small-cell lung cancer and EGFR signaling pathways.
- Deuterated small molecule designed for EGFR pathway research.
- Mesylate salt form with improved handling and solubility characteristics.
- Demonstrated decrease in p-EGFR and p-ERK levels in vitro.
- Shows antiproliferative and antitumor activity in preclinical models.
- Supplied in a 5 mg package suitable for analytical and in vitro studies.
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Medchemexpress LLC Gemifloxacin (mesylate) | 210353-53-0 | 99.7% | 50 MG
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Gemifloxacin mesylate is an orally active, broad-spectrum quinolone antibacterial antibiotic that inhibits DNA synthesis by targeting DNA gyrase and Topoisomerase IV activities. It exhibits potent antibacterial activities against gram-positive bacteria, particularly Streptococci and Staphylococci, and has been utilized in research for respiratory tract infections.
- Inhibits DNA gyrase and Topoisomerase IV activities
- Potent antibacterial activities against gram-positive bacteria
- Effective against Streptococci and Staphylococci
- Used in respiratory tract infection research
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Medchemexpress LLC Gemifloxacin mesylate | 210353-53-0 | 99.59% | 5 MG
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Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. It inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in in vitro efficacy study, particularly Streptococci and Staphylococci. It has been used in the research of respiratory tract infections.
- Inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities.
- Potent antibacterial activities against gram-positive bacteria in in vitro efficacy study, particularly Streptococci and Staphylococci.
- Used in the research of respiratory tract infections.
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Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | 99.9% | 500 MG
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Danofloxacin mesylate is a fluoroquinolone veterinary drug with a broad spectrum of bactericidal activity. Its primary mechanism of action involves inhibiting bacterial DNA gyrase. Additionally, it acts as a substrate for ATP-dependent efflux transporters, specifically P-gp and MRP2.
- Fluoroquinolone veterinary drug
- Broad spectrum bactericidal activity
- Inhibits bacterial DNA gyrase
- Substrate for ATP-dependent efflux transporters (P-gp and MRP2)
- Intended for research use only
- Inhibits bovine bacterial respiratory pathogens (e.g., Pasteurella hemolyticus, Pasteurella multocida, and Haemophilus somnosus)
- Exhibits asymmetric transport across Caco-2 cells
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eMolecules 5466-27-3 | ChemScene | Ethyl 2-hydroxyquinoline-4-carboxylate | 250mg | 654744479 | CS-0208320 | MFCD02041443 | 217.224 | C12H11NO3
ChemScene | Ethyl 2-hydroxyquinoline-4-carboxylate | 250mg | 654744479 | CS-0208320 | 5466-27-3 | MFCD02041443 | 217.224 | C12H11NO3
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Apexbio Technology LLC Proflavine Hemisulfate 1811-28-5 10mM (in 1mL DMSO)
Proflavine Hemisulfate (CAS 1811-28-5) is a small-molecule inhibitor targeting DNA It is designed to intercalate into DNA strands thereby disrupting DNA replication and transcription Proflavine Hemisulfate exerts its biological activity primarily through DNA intercalation In in vitro studies Proflavine Hemisulfate demonstrates antimicrobial activity with reported IC50 values for inhibiting bacterial growth typically ranging between 1 10 M depending on the microbial strain and assay conditions used Based on these pharmacological properties Proflavine Hemisulfate holds research potential in studies of antimicrobial activity DNA replication assays mutagenesis and evaluating sensitivity and resistance profiles of microorganisms
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eMolecules 14510-06-6 | Ambeed | 8-Hydroxyquinoline-2-carbaldehyde | 250mg | 525035238 | A130916 | MFCD00168962 | 173.171 | C10H7NO2
Medchem Express | 2-O4-C-Methyleneuridine | 10mg | 451965695 | HY-111639 | 200435-92-3 | 256.214 | C10H12N2O6
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eMolecules 2598-30-3 | Ambeed | 8-Hydroxyquinoline-5-carbaldehyde | 100mg | 506389925 | A268393 | MFCD03425064 | 173.171 | C10H7NO2
Ambeed | 13-Di(pyridin-2-yl)urea | 250mg | 525209246 | A424352 | 6268-43-5 | MFCD00233705 | 214.228 | C11H10N4O
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eMolecules 1260787-47-0 | 6-bromo-4-chloro-3-iodoquinoline | Synthonix | MFCD15527298 | 368.400 | C9H4BrClIN | 98.000 | Clc1c(I)cnc2ccc(Br)cc12 | 100mg | 784552098
6-bromo-4-chloro-3-iodoquinoline | Synthonix | 1260787-47-0 | MFCD15527298 | 368.400 | C9H4BrClIN | 98.000 | Clc1c(I)cnc2ccc(Br)cc12 | 100mg | 784552098
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Medchemexpress LLC RU.521 100mg | 2262452-06-0 | 100 MG
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RU.521 is a small-molecule inhibitor of cyclic GMP-AMP synthase (cGAS) used in research to suppress cGAS-mediated interferon signaling. It is supplied as a high-purity solid and is provided in multiple sizes and formulations for in vitro and cellular studies.
- High purity (99.95%) for reproducible results.
- Potent, selective inhibition of cGAS in cellular assays.
- Available in multiple sizes and DMSO solution formats for flexibility.
- Stable as a powder at -20°C for long-term storage.
- Molecular weight 415.23; formula C19H12Cl2N4O3.
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eMolecules LEUPEPTIN . HEMISULFATE 5MG
5000191507 LEUPEPTIN . HEMISULFATE 5MG
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